In many vertebrates, the enzymatic oxidation of dietary yellow carotenoids generates red keto‐carotenoids giving color to ornaments. The oxidase CYP2J19 is here a key effector. Its purported intracellular location suggests a shared biochemical pathway between trait expression and cell functioning. This might guarantee the reliability of red colorations as individual quality signals independent of production costs. We hypothesize that the ornament type (feathers vs. bare parts) and production costs (probably CYP2J19 activity compromising vital functions) could have promoted tissue‐specific gene relocation. (...) We review current avian tissue‐specific CYP2J19 expression data. Among the ten red‐billed species showing CYP2J19 bill expression, only one showed strong hepatic expression. Moreover, a phylogenetically‐controlled analysis of 25 red‐colored species shows that those producing red bare parts are less likely to have strong hepatic CYP2J19 expression than species with only red plumages. Thus, both production costs and shared pathways might have contributed to the evolution of red signals. (shrink)

Assessing physical fitness has emerged as a proxy of the health status of children and adolescents and therefore as relevant from a public health point of view. DAFIS is a project included in Plan Galicia Saudable of the regional government of Galicia. DAFIS consists of an on-line software devoted to record the results of a standard physical fitness protocol carried out as a part of the physical education curriculum. The aims of this study were: to obtain normative values of physical (...) fitness of the Galician school population evaluated in the DAFIS project, and to identify a reduced number of components and tests able to capture a significant amount of the variability in the physical fitness of children and adolescents. From an initial sample of 27784 records, 15287 cases were considered after filtering. Generalized Additive Models for Location, Scale and Shape were used for obtaining percentile curves and tables for each sex. Furthermore, a principal components analysis was performed, selecting the number of components by applying the Kaiser’s rule and selecting a subset of variables considering the correlation between each variable and the components. Percentile curves and normative values are reported for each test and sex. Physical fitness was better in boys than in girls throughout age groups, except for flexibility that was consistently higher in girls. Two main components were detected throughout age groups: the first one representing body composition and partially cardiorespiratory fitness and the second one muscular fitness. For boys and girls, waist to height ratio had the highest correlations with the first component in four out of six age groups. The highest correlation with the second component, was most frequently observed for the handgrip test both in boys and girls. This study provides evidence about the utility of school community actions like DAFIS aimed to track the health-related fitness of children and adolescents. The results suggest that fat mass distribution and muscular performance concentrate a high proportion physical fitness variance. (shrink)

Cognitive symptoms after COVID-19 have been increasingly recognized several months after the acute infection and have been designated as “brain fog.” We report a patient with cognitive symptoms that started immediately after COVID-19, in which cerebrospinal fluid biomarkers were highly suggestive of Alzheimer’s disease. Our case highlights the need to examine patients with cognitive symptoms following COVID-19 comprehensively. A detailed assessment combining clinical, cognitive, and biomarker studies may help disentangle the underlying mechanisms associated with cognitive dysfunction in each case. The (...) investigation of neurodegenerative processes in an early stage, especially in older patients, is probably warranted. (shrink)

Esta entrevista se realizó en dos sesiones vía Zoom, cuyas fechas están ubicadas en agosto de 2021. La primera conversación que se tuvo consistió en que el filósofo Modesto Gómez Alonso brindara unas ideas panorámicas y reflexivas, las cuales se han colocado al inicio de cada resolución. Entretanto, en la segunda conversación, se partió de lo planteado anteriormente y de algunos apuntes que permitieron esbozar de una forma más contundente las respuestas. Todo este procedimiento sirvió para que se pudiera (...) tratar sobre la noción de la epistemología desde sus múltiples manifestaciones. Es por eso por lo que el filósofo Modesto Gómez recurrió a concepciones afines, como aquellas que proporcionan el conocimiento, al igual que buscó explicar con mayor detalle al citar a autores como Descartes, Sosa, entre otros. En ese sentido, esta entrevista tuvo el propósito de buscar las conexiones que existen de la Filosofía con la vida cotidiana en cuanto a que se indaga de las posibilidades de contribuir al conocimiento y contar con las herramientas adecuadas. (shrink)

For the philosopher of Rotterdam, religious coercion has two essential sources of illegitimacy: the linking of religious and ecclesiastical belief and the use of politics for religious purposes. Bayle responds to it, with his doctrine of freedom of conscience, on one hand and by means of the essential distinction between voluntary religious affiliation and political obligation, on the other hand. From my perspective, his doctrine of tolerance does not involve an atheist state, nor does it mean the rejection of the (...) presence of religion in the public space or its displacement to the intimate sphere of the conscience. This paper proposes a reading of Baylean tolerance as a political doctrine that allows the articulation between freedom of conscience, minority confessions, and official religion. Thus, the Baylean theoretical model could be considered a proposal to provide a normative form to the practice of toleration present in the seventeenth -century Netherlands. (shrink)

En el presente artículo se abordarán las relaciones entre Nietzsche y Platón, y Nietzsche y Darwin, a partir de las respectivas autocalificaciones nietzscheanas –a saber, su propia filosofía como ‘platonismo invertido’, y su postura ‘anti-Darwin’. A partir de esto, se buscará alcanzar tres objetivos: en primer lugar, establecer que la calificación nietzscheana de ‘Anti-Darwin’ no se sustenta ni en una oposición de tipo ontobiológico, ni en oposición a un carácter teleológico de algún tipo, sino, principalmente, en una ruptura axiológica; en (...) segundo lugar, mostrar la conexión entre la perspectiva nietzscheana y el platonismo, en divergencia con las perspectivas que, o ponen a Nietzsche en completa oposición al platonismo, o encuentran concordancia no con el platonismo, sino con Platón, o hallan plena continuidad entre uno y otro –el ‘Nietzsche metafísico’ heideggeriano. Finalmente, el tercer objetivo consistirá en mostrar que ambas autocalificaciones se hallan estructuralmente asociadas, es decir, que una no es completamente comprensible sin la otra. (shrink)

We show that the properties of [relative] semisimplicity and congruence 3-permutability of a [quasi]variety with equationally definable [relative] principal congruences (EDP[R]C) can be characterized syntactically. We prove that a quasivariety with EDPRC is relatively semisimple if and only if it satisfies a finite set of quasi-identities that is effectively constructible from any conjunction of equations defining relative principal congruences in the quasivariety. This in turn allows us to obtain an ‘axiomatization’ of relatively filtral quasivarieties. We also show that a variety (...) is 3-permutable and has EDPC if and only if there is a single pair of quaternary terms satisfying two simple equations, and whose equality defines principal congruences in the variety. Finally, we combine both results to obtain a neat characterization of semisimple, 3-permutable varieties with EDPC, which is applied to solve a problem posed by Blok and Pigozzi in the third paper of their series on varieties with EDPC. (shrink)

This essay proposes that mathematical biology can be used as a fruitful exemplar for the introduction of scientific principles to history. After reviewing the antecedents of the application of mathematics to biology, in particular evolutionary biology, I describe in detail a mathematical model of cultural diffusion based on an analogy with population genetics. Subsequently, as a case study, this model is used to investigate the dynamics of the early modern European witch-crazes in Bavaria, England, Hungary and Finland. In the second (...) part of the article, I sketch the methodological significance of this type of 'scientific history' and, in particular, I identify three lessons that mathematical biology can contribute to historiography. The first lesson is on the fundamental distinction between agent's purposes and structural social processes. I argue that mathematical modeling can be fruitfully applied to describe social processes, while agents' purposes ought to be addressed following an hermeneutic tradition. The second lesson is on the aim of mathematical modeling. Here I argue that the object of modeling, rather than being the prediction or retrodiction of events , is the understanding of the factors involved in the dynamics of social processes . Finally, the third lesson is on the new understanding of science after the collapse of the standard view. In summary, while mathematical modeling can provide an extremely powerful approach to clarify the dynamics of certain macro-historical processes, scientific methods ought to be regarded as a complement, not a substitute, to classical historiography. (shrink)

Donald Davidson has claimed that for every logical truth 5 of a language L, a theory of meaning for L will entail that S is a logical truth of L. Jim Edwards has argued (2002) that this claim is false if we take 'entails' to mean 'has as a logical consequence. In this paper, I first show that, pace Edwards, Davidson's claim is correct even under this strong reading. I then discuss the argument given by Edwards and offer a diagnosis (...) of where he went wrong. (shrink)

Despite the emergence of computer games as a dominant cultural industry, we know little or nothing about the ethics of computer games. Considerations of the morality of computer games seldom go beyond intermittent portrayals of them in the mass media as training devices for teenage serial killers. In this first scholarly exploration of the subject, Miguel Sicart addresses broader issues about the ethics of games, the ethics of playing the games, and the ethical responsibilities of game designers. He argues (...) that computer games are ethical objects, that computer game players are ethical agents, and that the ethics of computer games should be seen as a complex network of responsibilities and moral duties. Players should not be considered passive amoral creatures; they reflect, relate, and create with ethical minds. The games they play are ethical systems, with rules that create gameworlds with values at play. Drawing on concepts from philosophy and game studies, Sicart proposes a framework for analyzing the ethics of computer games as both designed objects and player experiences. After presenting his core theoretical arguments and offering a general theory for understanding computer game ethics, Sicart offers case studies examining single-player games, multiplayer games, and online gameworlds from an ethical perspective. He explores issues raised by unethical content in computer games and its possible effect on players and offers a synthesis of design theory and ethics that could be used as both analytical tool and inspiration in the creation of ethical gameplay. (shrink)

In the last few decades, the study of terminology has undergone a cognitive shift that has led to the development of several approaches that study the social, linguistic, and cognitive dimension of terms, such as Communicative Theory of Terminology (CTT) and Frame-Based Terminology (FBT). CTT was developed in the early 1990s and argues that the study of terminology should be based on a communicative perspective, taking into account aspects such as the communicators and the context of communication. FBT has been (...) developed from 2007 and uses certain aspects of Frame Semantics to conceptualise specialised domains and create non-language-specific representations through the analysis of the domain event and on the study of the behaviour of the terminological units in texts. The two theories share many of the same premises and propose the representation of the concepts of a domain in an ontology. FBT also proposes a representation in frames. We explore how these two methods of domain representation can be used to represent the terminology of the domain of seafood in Germany and Spain. (shrink)

For most interpreters of the philosopher from Rotterdam, his political doctrine is solely a consequence of his religious and moral doctrines, and so an image of Bayle as a political philosopher is not usually presented. To my mind, however, only by analyzing his political doctrine can the extent of his religious proposal be understood. In this article, I intend to show that both the Baylean criticism of popular sovereignty and his rejection of the right of resistance are analyses that are (...) indissociable from the Baylean doctrine of tolerance. The protection of individual freedom of conscience and the defense of a multi-confessional state model, tolerant regarding religious minorities, can only be articulated as historical reality if they rest on the political doctrine of indivisible sovereignty and on the strictest separation between political obedience and religious membership. (shrink)

This article considers for the first time the progressive Portuguese periodicals A Voz Feminina and O Progresso from a transnational perspective, with particular reference to contemporary debates about women’s suffrage in England as well as the wider emergence of transnational women’s networks around that time. It discusses the epistolary contact of the Principal Editor, Francisca Wood, with key radical figures such as Lydia Becker in England, Marie Goegg in Switzerland and André Léo in France, through an analysis of relevant editorials, (...) articles and correspondence received from abroad and published in the pages of the journals. Furthermore, it casts light on how Francisca Wood and her enlightened husband, William Thorold Wood, invoked the ongoing support of prominent men such as John Stuart Mill for the cause of women’s rights. Such a pioneer early feminism in Portugal was particularly remarkable in the 1860s – a context preceding the socio-political and cultural debates staged publicly in the 1871 Casino Lectures by the “Geração de 70” – which, furthermore, all but sidelined the “Woman Question.” The article concludes with a brief discussion of whether, notwithstanding Wood’s invisibility at the point of her death in 1900, she may have been behind a symbolically significant cultural intervention: the first translation of Jane Eyre into Portuguese, published in instalments from 1877 onwards in O Zoophilo. (shrink)

El artículo señala la fascinación ejercida por la Matemática sobre algunos pensadores, antiguos y modernos, y sugiere una posible explicación basada en la utilidad de la Matemática, la certeza de sus afirmaciones y la elegancia de sus procedimientos.

The paper points out the fascination exerted by Mathematics on some thinkers, ancient and modern, and it poses a possible explanation based on the usefulness of Mathematics, the certainty of its statements, and the elegance of its procedures.

RESUMEN En el presente trabajo se buscará dar cuenta diagramáticamente del alcance y extensión del concepto de vida en Freud y Nietzsche, al pensar sus límites en términos de polos -instancias no alcanzables vitalmente, que marcan la frontera a partir de la cual se extiende el ‘más allá’ de la vida. Dicho de otro modo: haciendo uso de un diagrama, se buscará dar cuenta del carácter de lo vital para Nietzsche - al pensar a la vida como Wille zur Macht (...) - y Freud - desde su último modelo pulsional - no solo en cuanto a su particularidad, sino en función de lo que resulta en cada caso el límite mismo de la vida - es decir, aquello que marca el pasaje a otra cosa que la vida. ABSTRACT In the present work, we will seek to give a diagrammatic account of the scope and extension of the concept of life in Freud and Nietzsche, by thinking about its limits in terms of poles - vitally unreachable instances, which mark the border from which the ‘beyond ‘of life extends itself. In other words: making use of a diagram, we will seek to account for the character of what is vital for Nietzsche - thinking of life as Wille zur Macht - and Freud - from their latest drive model - not only in terms of their particularity, but rather as a function of what the very limit of life results in each case - it means, that which marks the passage to something other than life. (shrink)

La propuesta ético-política foucaulteana proyectada en torno al cura sui, a partir de la práctica de la parrhesía, ha sido criticada en términos de un puro hacer solipsista, que no busca resistir al poder sino desde una disposición estética individual. Partiendo de una mención foucaulteana —la parrhesía se acerca al modo nietzscheano de pensar la verdad desde el riesgo— buscaremos mostrar dos puntos: que dicha cercanía es pensable desde una comparación entre las relaciones de poder foucaulteanas y de lucha nietzscheanas, (...) lo cual permite concebir el cura sui de un modo más amplio; y que la diferencia desplegada en la concepción de dichas relaciones de poder y de lucha es articulable desde lo que les es, correspondientemente, antagónico en términos ético-políticos: en Foucault, el poder como dominación y en Nietzsche, la civilización heredera de los valores cristianos. (shrink)

At the present paper it will be pursued to give account of how discursiveness is configured in the works of Nietzsche and Freud around the notion of life from a Freudian concept, that of underpinning. From the same, the particular discursive field relative to the vital will be characterized ―both in Freud and Nietzsche― as hybrid field ―meaning, a field that does not subscribe to any particular epistemological canon― thus giving account that innovation is produced not only when thinking the (...) very concept, but also when constructing the discourse. (shrink)

En el presente trabajo se buscará abordar la relación entre las obras de Nietzsche y Freud y el arte a partir de dos líneas de análisis: en primer lugar, el modo particular en que, para cada autor, se despliega la relación del arte con el plano social; en segundo lugar, que la noción misma de arte se halla íntimamente ligada al modo en que, para cada uno, se caracterizan la percepción y al concepto mismo de vida. Finalmente, se trazará una (...) articulación entre ambas líneas analíticas: el modo particular en que el arte es, para ambos autores, pensado en términos sociales, se sustenta –a través de la manera en que es concebida la percepción- a partir del concepto mismo de vida. Esta articulación permitirá fundamentar cómo es que Freud mantiene una relación sintónica con el arte clásico, mientras que la perspectiva nietzscheana, por el contrario, resulta sintónica con el arte de vanguardia. (shrink)

Al abordar las relaciones entre los pensamientos de Freud y Nietzsche, la reflexión sobre el lugar que ocupan el placer y el displacer ha sido desarrollada de modo escaso o tangencial. El objetivo central de este artículo será dar cuenta de cómo, a partir de una lectura de la dinámica vital en ambos autores en función de las relaciones placer-displacer, es posible ubicar un espacio ‘más allá’ de las mismas que definirá dicha dinámica en términos de dominio (Bewältigung). A partir (...) de ello, se buscará mostrar cómo el Bewältigung presenta tendencias divergentes para cada pensador en función de cómo se concibe la relación entre ser vivo y las fuerzas que le son internas y externas. (shrink)

La temática del lenguaje en Nietzsche ha sido abordada ampliamente, ya sea como problema epistemológico en sí, o en conexión con otros conceptos claves de su obra. En el presente trabajo, se abordará dicha temática desde la preocupación que Nietzsche muestra por la validez que su propio lenguaje posee al exponer sus ideas –fundamentalmente, aquella de una vida ascendente. Para ello, se recorrerá la obra nietzscheana desplegando la relación entre dicha idea y el tipo de lenguaje utilizado, partiendo desde El (...) nacimiento de la tragedia, a través de Humano, demasiado humano, para arribar a Así habló Zarathustra –donde Nietzsche declara haber alcanzado su ‘lenguaje propio’. Desde la respuesta a la pregunta de por qué, en sus obras posteriores, ese lenguaje tan buscado es abandonado, intentaremos mostrar –en la conclusión- cómo, en el uso nietzscheano hacia dentro de su propia obra, el lenguaje mismo adquiere el carácter de herramienta táctica. (shrink)

Recently, many normative theories of democracy have taken an epistemic turn. Rather than focus on democracy's morally desirable features, they argue that democracy is valuable (at least in part) because it tends to produce correct political decisions. I argue that these theories place epistemic demands on citizens that conflict with core democratic commitments. First, I discuss a well-known challenge to epistemic arguments for democracy that I call the ‘deference problem’. I then argue that framing debates about this deference problem in (...) terms of work on epistemic defeat reveals a structurally similar but more serious challenge for epistemic arguments for democracy. Succinctly put, the problem is that if democracy tends to produce correct political decisions, then those in the minority might be required to suspend beliefs about political matters; however, this requirement conflicts with the pivotal democratic principle of self-government. Call this the ‘suspension problem’. (shrink)

This paper is concerned with the semantics of bare plural I-generics such as ‘Tigers are striped’, ‘Chickens lay eggs’, and ‘Kangaroos live in Australia’. In a series of recent papers, Bernhard Nickel has developed a comprehensive view of a certain class of bare plural I-generics, which he calls characterizing sentences :629–648, 2009. doi:10.1007/s10988-008-9049-7; Linguist Philos 33:479–512, 2010a. doi:10.1007/s10988-011-9087-4; Philos Impr 10:1–25, 2010b). Nickel’s ambitious proposal includes a detailed account of their truth-conditions, an account of certain pragmatic phenomena that they give (...) rise to, a metaphysical picture of their truth-makers in terms of mechanisms, and an epistemological story connecting characterizing sentences to such concepts as induction and explanation. This paper offers an extended critique of the central truth-conditional component of Nickel’s proposal. In a nutshell, his account has it that ‘Tigers are striped’ is true iff, for tigers, there is a way of being normal with respect to fur-pattern such that all tigers that are normal that way are striped. I begin by explaining what characterizing sentences are and distinguish several readings that are available for sentences with bare plurals in subject position. I then introduce Nickel’s account and discuss some of its predictions which, in my view, seem highly problematic. Moreover, I argue that Nickel’s principle of Homogeneity does not go together well with his proposed truth-conditions, and that his truth-conditional account violates a plausible principle about the logic of generics, a principle I call generic non-contradiction. (shrink)

Desde tiempos inmemoriales, filosofía y teoría política han deambulado por senderos paralelos: en unas ocasiones, prestándose armas mutuamente; en otras, sin embargo, arrinconándose y asfixiándose. A causa de la complejidad de los sucesos acaecidos en el pasado siglo XX, a aquella conflictiva pero siempre enriquecedora relación se unieron compañeras como la teología, la sociología o la antropología, que desearon aportar algo de luz en el opaco contexto de las guerras mundiales, el desarrollo del nazismo, la Revolución rusa, la emergencia de (...) los fascismos, etc. En este novedoso libro, Roberto Navarrete Alonso se ocupa de dos figuras coetáneas y del todo fundamentales: Carl Schmitt (1888-1985) y Franz Rosenzweig (1886-1929). El autor se propone, a partir del estudio conjunto de estos pensadores, reflexionar sobre el Holocausto, sobre la Shoah o Catástrofe, abriendo de nuevo el insoslayable problema de la vertiente política del mal y su acaecimiento en la historia. El presente volumen se hace cargo de un nexo tan capital como inexplorado en el seno del pensamiento político-filosófico de comienzos del XX, analizando las fuentes, los cruces, los encuentros y desencuentros que tuvieron lugar entre Schmitt –referencia inexcusable de la reflexión jurídico-política del pasado siglo– y Rosenzweig –autor de la La estrella de la redención–. (shrink)

El presente trabajo investiga las tesis sobre el poder civil de Alonso de la Veracruz que buscan incorporar en la comunidad política española a los habitantes autóctonos del Nuevo Mundo, tesis que suelen relacionarse con F. de Vitoria y el tomismo español, y que últimamente son consideradas parte del republicanismo novohispano elaborado desde la periferia americana. Se busca demostrar que su propósito era aplicar una teoría de derechos naturales, sin que ello implique participación política de los indios americanos. Se (...) analiza la postura del fraile frente a la diversidad cultural y la guerra contra los indios. The paper explores Alonso de la Veracruz's theses on civil power, which sought to integrate the native inhabitants of the New World into the Spanish political community. These theses, which have usually been associated with F. de Vitoria and Spanish Thomism, have recently come to be considered part of a Novohispanic republicanism developed in the American periphery. The article seeks to show that the purpose of such theses was to apply a theory of natural rights that did not entail the political participation of the indigenous population, as well as to analyze Veracruz's position regarding cultural diversity and the war against the indigenous peoples. (shrink)